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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP2A1
All Species:
39.39
Human Site:
Y497
Identified Species:
78.79
UniProt:
O14983
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14983
NP_004311.1
1001
110252
Y497
D
R
K
S
M
S
V
Y
C
S
P
A
K
S
S
Chimpanzee
Pan troglodytes
XP_001142958
1000
109764
Y496
D
R
K
S
M
S
V
Y
C
S
P
A
K
S
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849777
993
109198
Y497
D
R
K
S
M
S
V
Y
C
S
P
A
K
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R429
994
109407
Y497
D
R
K
S
M
S
V
Y
C
S
P
A
K
S
S
Rat
Rattus norvegicus
Q64578
994
109391
Y497
D
R
K
S
M
S
V
Y
C
S
P
A
K
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505463
1167
128710
Y667
D
R
K
S
M
S
V
Y
C
T
P
N
K
P
S
Chicken
Gallus gallus
P13585
994
109005
Y497
D
R
K
S
M
S
V
Y
C
S
P
A
K
A
S
Frog
Xenopus laevis
NP_001080404
996
109455
Y497
D
R
K
S
M
S
V
Y
C
T
P
A
K
A
S
Zebra Danio
Brachydanio rerio
NP_001007030
994
108738
Y497
D
R
K
S
M
S
V
Y
C
S
P
A
K
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22700
1020
111683
Y497
D
R
K
S
M
S
S
Y
C
T
P
L
K
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SY55
998
109042
K494
L
E
F
T
R
D
R
K
M
M
S
V
L
C
S
Baker's Yeast
Sacchar. cerevisiae
P13586
950
104552
P476
V
Q
K
V
Q
E
L
P
F
N
S
K
R
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96
N.A.
95.5
N.A.
95.9
96
N.A.
71.1
90.2
89.1
85.2
N.A.
69.8
N.A.
N.A.
N.A.
Protein Similarity:
100
97.1
N.A.
98
N.A.
97.9
98
N.A.
79
95
95.5
92.2
N.A.
81.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
80
93.3
86.6
93.3
N.A.
73.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
100
N.A.
86.6
100
100
100
N.A.
86.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
55.5
31.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
71.2
52.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
67
0
34
0
% A
% Cys:
0
0
0
0
0
0
0
0
84
0
0
0
0
9
0
% C
% Asp:
84
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
92
0
0
0
0
9
0
0
0
9
84
9
0
% K
% Leu:
9
0
0
0
0
0
9
0
0
0
0
9
9
0
9
% L
% Met:
0
0
0
0
84
0
0
0
9
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
9
0
0
84
0
0
9
0
% P
% Gln:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
84
0
0
9
0
9
0
0
0
0
0
9
0
9
% R
% Ser:
0
0
0
84
0
84
9
0
0
59
17
0
0
42
84
% S
% Thr:
0
0
0
9
0
0
0
0
0
25
0
0
0
0
0
% T
% Val:
9
0
0
9
0
0
75
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _